Correlation between Physical Activity and Arterial Stiffness in Korean Office Workers: A Community-Based Study

Arterial stiffness is one of the most important determinants of increased systolic arterial pressure and pulse pressure, and is closely associated with hypertension, hyperlipidemia, type 2 diabetes melli-tus, and artery hardening (1-2). The American College Sports Medicine guideline states regular exercise can prevent and treat cardiovascular system dysfunction including arterial stiffness (3). However , the meta-analysis of Williams (2001) shows physical fitness level owing to regular exercise and levels of daily physical activity (PA) are independent cardiovascular risk factors (4). As PA has also been reported to protect the cardiovascular system via increased physical fitness level, additional studies are required to clarify the associations between PA level and cardiovascular risk factors. In particular , the association between PA and arterial stiffness requires clarification. Therefore, this study investigated the association between PA level and arterial stiffness in Korean office workers. This study evaluated 487 male and 325 female Korean office workers who visited a Seoul-City Hall in Seoul, Republic of Korea and signed a written informed consent form. PA level and pulse wave velocity were measured. PA level was assessed by using the International Physical Activity Questionnaire (IPAQ) (5-6) as follows: (a) walking (metabolic equivalents of task [MET]·min·week −1) = 3.3 × walking minutes × walking days; (b) moderate PA (MET·min·week −1) = 4.0 × moderate PA minutes × moderate days; (c) vigorous PA (MET·min·week −1) = 8.0 × vigorous PA minutes × vigorous days; (d) total PA (MET·min·week −1) = walking + moderate PA + vigorous PA. Pulse wave velocity was determined by a pulse waveform analyzer (PV-1000, Colin-Co, Ltd., Komaki, Japan) according to the recommendations of Van Bortel et al. (7). No participants exercised regularly or had any health problems. Partial correlation coefficients were used to adjust for age and body mass index when analyzing the correlation between PA level and arterial stiffness. The level of significance was set at P < 0.05. All analyses were performed using SPSS version 18.0 The baseline characteristics of the participants are presented in Table 1. PA was not significantly correlated with arterial stiffness in men (r = 0.060, P = 0.189) or women (r = 0.047, P = 0.403) (Table 2). Weekly sedentary time was not significantly correlated with arterial stiffness in men (r = −0.055, P = 0.231) but was significantly correlated with arterial stiffness in women (r = 0.195, P < 0.001). The results of this study indicate PA is …